Desert Orthopaedic Center - Rancho Mirage

John DeSantis, DO
Current Appointment

Orthopedic Surgeon at Desert Orthopedic Center


Hip & Knee Reconstruction

John G. DeSantis, D. O., is a board certified fellowship-trained orthopedic surgeon specializing in total hip and total knee reconstruction. A native of Michigan, Dr. DeSantis moved to Southern California to join Desert Orthopedic Center in 2008. Prior to moving to Rancho Mirage, Dr. DeSantis practiced in Michigan where he had established the Knee and Orthopedic Center in 1988 after completion of his fellowship in Florida.

Dr. DeSantis has successfully performed thousands of hip and knee surgeries including arthroscopic knee surgery, total hip replacement and hip resurfacing, total knee and partial knee replacement, custom knee replacement, revision hip and revision knee replacement, bilateral knee replacement and combined hip and knee replacement surgery. Dr. DeSantis performs hip surgeries through the “bikini incision” anterior approach. The biggest advantage for his patients is that this allows immediate freedom in their hip range of motion and early return to their desired activities. He prefers this approach as patients are not required to follow traditional hip precautions which limit hip flexion and range of motion postoperatively.

Dr. DeSantis graduated from Michigan State University College of Osteopathic Medicine and completed an orthopedic residency at Detroit Osteopathic/Bi County Community Hospital in Michigan. He is a Diplomat of the National Board of Examiners and has served as an oral examiner for the AOA Orthopedic Certification Examination. He is a member of the American Medical Association, the American Osteopathic Academy of Orthopedics, American Osteopathic Association, the American Osteopathic Academy of Sports Medicine and the American Association of Hip and Knee Surgeons.


Desert Orthopaedic Center - Rancho Mirage

39000 Bob Hope Dr. Harry & Diane Rinker Bldg Rancho Mirage, CA 92270

(760) 205-2620
Desert Orthopaedic Center - La Quinta

45280 Seeley Dr. Eisenhower George & Julia Argyros Health Center La Quinta, CA 92253

(760) 205-2620
Contact Us
Find surgeon